Saffron: Menopause Superhero

Have you ever wondered why the Menopause capsule in Nu Mind Well is such a vibrant colour? Simple, we include a whopping 30mg of saffron in each capsule.

Have you ever wondered why the Menopause capsule in Nu Mind Well is such a vibrant colour? Simple, we include a whopping 30mg of saffron in each capsule.

Saffron (Crocus sativus) is a highly prized spice derived from the stigmas of the Crocus sativus flower. Its bright colour, distinct flavour, and aroma have made it a popular ingredient in culinary traditions worldwide. However, saffron is not just a culinary delight; in recent years, scientific research has shed light on saffron's medicinal and therapeutic health benefits, particularly in menopause.

Saffron possesses anti-inflammatory, antioxidant, and neuroprotective properties (Srivastava, 2010). It may support various health problems, including infections, pain, inflammation, chronic fatigue, insomnia, memory impairment, mood, and mental health disorders such as anxiety, depression. The therapeutic activity of C. sativus extracts in alleviating inflammation and central nervous system disorders, including depression, has been confirmed in the most recent basic animal (rodent) studies and human clinical trials (Matraszek-Gawron, 2023).

In the specific context of menopause, saffron has shown promise in addressing several symptoms commonly associated with this life stage. One of the most significant challenges faced by menopausal women is the management of mood disturbances, including anxiety and depression. Clinical studies have indicated that saffron supplementation can lead to notable improvements in mood and psychological symptoms.

For instance, a randomized, double-blind, placebo-controlled trial conducted on overweight women with mild to moderate depression demonstrated that saffron supplementation at a dosage of 30mg per day led to a significant reduction in anxiety by 33% and depression by 32% over 12 weeks (Hausenblas, 2015). These findings suggest that saffron, as a safe over-the-counter supplement, may offer relief for individuals experiencing mild to moderate depression, particularly those who are overweight.

Moreover, saffron has shown potential in managing hot flushes, a common symptom experienced by menopausal women. Hot flushes, characterized by sudden intense heat and sweating, can be debilitating, and negatively impact quality of life. A randomized, double-blind, placebo-controlled trial on postmenopausal women with hot flushes revealed that saffron supplementation reduced both hot flushes and depressive symptoms over six weeks (Mazidi, 2016).

Although the effects on other menopausal symptoms and overall quality of life were not substantial, the results highlight the potential of saffron as an adjunctive therapy for managing hot flushes. Despite the promising findings, it is essential to acknowledge that further research is needed to establish the full benefits of saffron in managing menopausal symptoms.

References

Matraszek-Gawron, R., Chwil, M., Terlecki, K. and Skoczylas, M.M. (2023). Current Knowledge of the Antidepressant Activity of Chemical Compounds from Crocus sativus L. Pharmaceuticals, 16(1), p.58. doi:https://doi.org/10.3390/ph16010058.

Hausenblas, H., Heekin, K., Mutchie, H.L. and Anton, S. (2015). A systematic review of randomized controlled trials examining the effectiveness of saffron (Crocus sativus L.) on psychological and behavioral outcomes. Journal of Integrative Medicine, 13(4), pp.231–240. doi:https://doi.org/10.1016/s2095-4964(15)60176-5.

Mazidi, M., Shemshian, M., Mousavi, S.H., Norouzy, A., Kermani, T., Moghiman, T., Sadeghi, A., Mokhber, N., Ghayour-Mobarhan, M. and Ferns, G.A.A. (2016). A double-blind, randomized and placebo-controlled trial of Saffron (Crocus sativus L.) in the treatment of anxiety and depression. Journal of Complementary and Integrative Medicine, 13(2). doi:https://doi.org/10.1515/jcim-2015-0043.

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